SESSION III. Pathology of Diabetes
Mellitus
A. Insulin
1.
Biochemistry
2. Sources:
a. Animal
b. Human
B. Primary
Idiopathic Diabetes:
1. Type I:
Insulin-dependent diabetes mellitus (IDDM)
a. Hystological
images of pancreatic islets with insulitis
b. Immunofluorescence
of NOD pancreatic islet with insulitis (T cells
and insulin markers).
2. Type II: Non-insulin-dependent diabetes mellitus (NIDDM):
a. Non-obese
NIDDM
b. Obese NIDDM
c. Maturity-onset diabetes of the young (MODY)
3. Table
of Comparison between Type I and Type II
C. Secondary
Diabetes:
1. Chronic
pancreatitis
2. Post-pancreatectomy
3. Hormonal tumors (e.g. pheochromocytoma, pituitary
tumors)
4. Hemochromatosis
5. Genetic disorders (e.g. Lipodystrophy)
D. Laboratory
Diagnosis of Diabetes Mellitus
1. Glucose
tests:
a. Fasting
b. Postprandial
c. Tolerance tests
d. Other tests
2. Insulin
tests
3. Other complementary tests
E. Complications
of diabetes
1.
Microangiopathy
2. Retinopathy
3. Nephropathy
4. Neuropathy
F. Treatment of
diabetes
1. Treatment
of hyperglycemia
2. Treatment of hypoglycemia
3. Treatment of complications
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