Mariano Alvira, M.D. Pathologist (AP/CP) Spain - USA

BORN: Zaragoza, Spain.

LICENSURE: E.C.F.M.G., 1968, F.L.E.X., 1973; Illinois, 1973; Ohio, 1976.

CERTIFICATION: American Board of Anatomical and Clinical Pathology, 1974; American Board of Neuropathology, 1977

SPECIALIZATION: Informatics, Surgical Pathology, Electron Microscopy.

INTERNSHIP: 1969-70, Rotating Internship, Evanston Hospital, Evanston, Illinois.

RESIDENCY: 1970-74, Anatomic and Clinical Pathology, Evanston Hospital, Evanston, Illinois.

FELLOWSHIP: 1974-75, Clinical Fellow in Neuropathology, Department of Pathology, University of Cincinnati, Cincinnati, Ohio.

UNIVERSITY OF CINCINNATI: 1975-77, Associate Pathologist, Neuropathologist, Department of Pathology, Medical College, University of Cincinnati, Cincinnati, Ohio.

E-mail:

          alviram@infinet.com

EDUCATIONAL EXPERIENCE:

UNDERGRADUATE: 1959-61, University of Zaragoza, School of Sciences, Spain.

MEDICAL: 1961-68, Complutense University, School of Medicine, Madrid, Spain.

POST-DOCTORAL: 1968-69, Complutense University, School of Medicine, Madrid, Spain.

ACADEMIC APPOINTMENTS:

1973-74, Instructor of Pathology Medical School, Northwestern University.

1975-77, Assistant Professor of Pathology, Medical College, University of Cincinnati.

1975-77, Consultant Neuropathologist for the Mayfield Neurological Institute, Cincinnati, Ohio.

1977-81, Assistant Clinical Professor of Pathology, Medical College, University of Cincinnati.

AWARDS:

1969: Travel Grant (Fulbright Grant), Commission for Education Exchange between the United States of America and Spain, supervised by the Institute of International Education.

1972-74: Research Grant, "Histochemistry of brain: silver carbonate impregnation",the Thomas J. Dee and George G. Moody Research and Education Fund, Evanston Hospital, Evanston, Illinois.

1971: Second prize, annual House Staff Research Paper Contest, Evanston Hospital, Evanston, Illinois.

1972: Third prize, annual House Staff Research Paper Contest, Evanston Hospital.

1973: Honorable Mention, Hektoen Award, Chicago Pathological Society, Chicago, Illinois.

1974: First prize, Hektoen Award, Chicago Pathological Society, Chicago, Illinois.

MEMBERSHIP:

College of American Pathologists, 1983- present.

PUBLICATIONS:

• Alvira MM and Forman DT: Biochemical abnormalities in Reye's syndrome. Ann. Clin. Lab. Science 4: 477-483, 1974.
  
  
• Alvira MM, Mandybur TI and Menefee MG: Light microscopic and ultrastructural observations of a metastatizing malignant epitheliod schwannoma. Cancer 38:1977-1982, 1976.
  
  
• Linnemann C, First MR, Alvira MM, Alexander JW and Schiff GM: Herpes virushominis type 2 meningoencephalitis following renal transplantation. Am. J. Med. 61: 703-709,1976.
  
  
• Alvira MM and McLaurin RL: Asymptomatic subdural chondrosarcoma: a case report. J.Neurosurgery 48: 825-828, 1978.
  
  
• Linnemann C, Dunn CR, First MR, Alvira MM and Schiff GM: Late onset of fatal cytomegalovirus infection after renal transplantation. Primary or reactivation infection. Arch. Intern. Med. 138: 1247-1250, 1978.
  
  
• Schima T, Keller JT, Alvira MM, Dunsker SB and Mayfield FH: Anterior cervical discectomy and interbody fusion. An experimental study using a synthetic tricalcium phosphate. J. Neurosurgery 51: 533-538, 1979.
  
  
• Linnemann C and Alvira MM: Pathogenesis of varicella-zoster infection in the central nervous system. Arch. Neurol. 37: 239-240, 1980.
  
  
• Kauffman CA, Linnemann C and Alvira MM: Cytomegalovirus encephalitis associated with thymoma and immunoglobulin deficiency. Am. J. Med. 67:724-728, 1979.
  
  
• Mandybur TI and Alvira MM: Ultrastructural findings in so-called ependymal rat tumors induced by transplacental administration of ethylnitrosourea. Acta Neuropathol. (Berl) 57: 51-58, 1982.
  
  
• Weiss MA, Rolfes DB, Alvira MM and Cohen LJ: Benign lymphocytic angiitis and granulomatosis: a case report with evidence of an autoimmune etiology. Am. J. Clin. Pathol. 81: 110-116, 1984.
  
  
• Juberg RC, Christopher CR, Alvira MM and Gilbert EF: Clinicopathologic conference: trisomy 10q/monosomy 12p in one dysmorphic, dizygous twin of a T(10; 12) (10p12p; 10q12q) mother. Am. J. Med. Genetics 18:201-213, 1984.
  
  
• Woodward PM, Metcalf DW and Alvira MM: Ultrastructural studies of the effects of neodymiun:yag laser anterior capsulotomy on the ciliary epithelium of the rabbit. Ophthal. LaserTherapy1:153-168, 1986.
  
  
• Alvira MM: 19 Year Old Male with Frontal Lobe Tumor. Brain Pathology 8: 409-410 (1998).
  

ABSTRACTS:

• Forman DT and Alvira MM: Measurements of isoenzymes of serum creatine phosphokinase for the diagnosis of Brain-Reye's syndrome. Presented to the Association of Clinical Scientists, March 9, 1974, La Jolla, CA.
  
  
• Alvira MM and Forman DT: Encephalopathy and fatty degeneration of the viscera (EFDV): Biochemical characterization. Am. J. Clin. Path. 63:600, 1975.
  
  
• Forman DT, Alvira MM, Grayson SH and Kirkpatrick PB: Biochemical aspects of Reye's syndrome. Clin. Chem. 20: 865, 1974.
  
  
• Alvira MM and Mendoza M: Reye's syndrome: A viral myopathy?. New Eng. J. Med.292: 1297, 1975.
  
  
• Mendoza M, Alvira MM and Smith RD: Viral crystalline arrays in Reye's syndrome. Am. J. Clin. Path. 65: 262-63, 1976.
  
  
• Alvira MM, Mendoza M and Mandybur TI: Abnormal unit membranes and subunit periodicity in human spongiforme encephalopathy. (Creutzfeldt-Jacob disease). J. Neuropath. and Exp. Neurol. 35: 317,1976.
  
  
• Alvira MM, Mendoza M and Chedid A: The fine structure of altered membranes in Creutzfeldt-Jacob disease. Presented to the XI World Congress of the International Academy of Pathology in Washington D.C.,November 19,1976.
  
  
• Alvira MM, Shebbabian S, Lukin R and Tew JM: The pathology of surgically treated cryptic arteriovenous malformations (AVM). Am. J. Clin. Path. 70: 330-31, 1978.
  
  
• Alvira MM, Tew JM and Lukin R: Unusual myelin structure in a case of adreno-leukodystrophy. J. Neuropath. and Exp. Neurol. 37: 584, 1978.
  
  
• Alvira MM: Particulate osmiophilic membranous structures (POMS) in Creutzfeldt-Jacob disease. FASEB, 1977.
  
  
• Jimenez JF and Alvira MM: Glandular differentiation of bronchogenic epidermoid carcinoma in central nervous system metastases. J. Neuropath. and Exp. Neurol. 37:636, 1978.
  
  
• Alvira MM, Mandybur TI and Liwnicz BH: Some ultrastructural findings in central nervous system tumors induced by transplacental administration of ENU in the rat. J. Neuropath. and Exp. Neurol. 38:303, 1979.
  
  
• Liwnicz BH, Mandybur TI and Alvira MM: ENU-induced granular oligodendroglioma in the rat. J. Neuropath. and Exp. Neurol. 38: 329,1979.
  
  
• Alvira MM and Orcutt MJ: The clinicopathological spectrum of collagenous colitis. Am. J. Clin. Pathol. 81: 390, 1984.
  

PRESENTATIONS AND SEMINARS:

• Encephalopathy and fatty degeneration of the viscera (EFDV): Biochemical characterization. Presented at the Spring Meeting of the American Society of Clinical Pathologists, 1975, Chicago, Illinois,USA.
  
  
• Abnormal unit membranes and subunit periodicity in human spongiforme encephalopathy. (Creutzfeldt-Jacob disease). Presented at the Spring Meeting of the American Association of Neuropathologists, 1976, San Francisco, California, USA.
  
  
• The fine structure of altered membranes in Creutzfeldt-Jacob disease. Presented to the XI World Congress of the International Academy of Pathology and Second World Congress of Academic and Environmental Pathology, 1976, Washington D.C., USA.
  
  
• Particulate Osmiophilic Membranous Structures (POMS) in Creutzfeldt-Jacob Disease. Spring Meeting of the FASEB, 1977, Washington D.C., USA.
  
  
• The Pathology of Surgically Treated Cryptic Arteriovenous Malformations (AVM). Presented at the Spring Meeting of the American Society of Clinical Pathologists, 1978, Dallas, Texas, USA.
  
  
• Alzheimer's Disease. Conference presented at the Annual Meeting of the Ohio Sate Coroners Association, Spring 1983, Cincinnati, Ohio, USA.
  
  
• The Clinicopathological Spectrum of Collagenous Colitis. Presented at the Spring Meeting of the American Society of Clinical Pathologists, 1983, Chicago, Illinois, USA.
  
  
• Digital Imaging in Pathology. Spring Meeting Workshop of the American Society of Clinical Pathologists,1993, Chicago, Illinois, USA.
  
  
• Plug Your Microscope Into Your Planet PC-Tumor Bulletin Board System. Fall Meeting Exhibit of the American Society of Clinical Pathologists, 1993, Orlando, Florida, USA.
  
  
• Alvira MM and Kepes JJ: Cerebral metastasis of anaplastic prostatic carcinoma mimicking glioblastoma multiforme. International Congress of Neuropathology, Fall 1994, Toronto, Canada.
  
  
• Online94. Fall Seminar of the American Society of Clinical Pathologists, 1994, Washington D.C.,USA.
  
  
• PC-Tumor BBS (407) 234-1287. Fall Meeting Exhibit of the American Society of Clinical Pathologists, 1994, Washington D.C.
  
  
• Digital Imaging in Pathology. Fall Meeting Workshop of the American Society of Clinical Pathologists,1994, Washington D.C.,USA.
  
  
• Digital Imaging in Pathology. Spring Meeting Workshop of the American Society of Clinical Pathologists,1996, Boston, Massachusetts, USA.
  
  
• Digital Imaging in Pathology. Spring Meeting Workshop of the American Society of Clinical Pathologists,1997, Chicago, Illinois, USA.
  
  
• Digital Imaging in Pathology. Spring Meeting Workshop of the American Society of Clinical Pathologists,1998, Los Angeles, California, USA.
  

CYBERSPACE:

• Member and Contributor of the PC-Tumor BBS, 1992.
  
  
• Member and Contributor of the Tumorboard, 1996: http://www.tumorboard.com
  
  
• Member and Contributor of the Society of Ultrastructural Pathologist,1996: http://zappa.ultrakohl.com
  
  
• Contributor to Brain Pathology,1998: http://brainpathology.upmc.edu.us
  
  
• Contributor to III Virtual Congress of Hispano-American Anatomic Pathology, 2000: http://conganat.uniovi.es
  
  
• Chairman of Uropathology and Contributor to the VI Virtual Symposium Congress of Biomedical Sciences, 2000: http://www.uclm.es/inabis2000/symposia
  
  
• Webmaster of the Tumorboard, 1999: http://www.tumorboard.com
  

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